I have both an APC40 and APC Mini, and neither is of much use except in Ableton Live, and even in Live, I can’t use both controllers at once. I’ve also found that they’re both pretty useless in VCVRack because of the way the MIDI works.
You can’t - for example - map the channel faders on an APC40 to the channel faders on a Mindmeld Mixmaster. Each of the channels uses the same CC/Note values in different MIDI channels.
EDIT: The APC40 is even screwier than that. The 8 channel faders are the standard VOLUME CC on channels 1-8 but the master volume is Controller 14 on channel 1.